Transient Global Amnesia as a Presentation of Frontal Lobe Meningioma – A Case Report

Abstract

Meningiomas are amongst the most common primary brain tumors, accounting for around one third of cases. They usually present with focal neurological deficits, signs of raised intracranial pressure or seizures. Transient global amnesia (TGA) is an uncommon disorder, usually linked with severe emotional or physical stress, migraine variant or vascular risk factors. It is believed to originate from hippocampal dysfunction. We present the case of a 65 year female, who visited our hospital with two episodes of transient amnesia. Both episodes lasted for 4-5 hours with no other focal neurological dysfunction noted. She fit the diagnostic criteria for TGA and seizures were ruled out by a normal sleep-deprived electroencephalogram (EEG). Magnetic Resonance Imaging (MRI) of Brain showed the presence of a right frontal meningioma. We conclude that she suffered from TGA secondary to right frontal meningioma, a rare association of which only a handful of cases have been reported worldwide.