Role of Myo-Inositol in Treatment of Young Females Affected By Polycystic Ovarian Syndrome: Quasi Experimental Study

Abstract

Objective: To determine the effects of Myo- inositol in young females with polycystic ovarian syndrome. Study Design and Setting: This was a quasi-experimental study and was conducted in United Medical and Dental College and Creek General Hospital from January 2017 to January 2018. Methodology: Total 100 patients were recruited based on the specific inclusion criteria of PCO diagnosed by symptoms (body mass index, menstrual irregularity, hirsutism, acne) biochemical markers (fasting insulin, random blood sugar) and ultrasound findings. Each subject in the study group was given sachet (Myo- inositol 2000mg and folic acid 400ug) once a day dissolved in glass of water for duration of 6 months. Improvement in symptoms, biochemical markers and ultrasound findings were reassessed after the completion of 6 months duration. The SPSS version 21 was used for data analysis. The paired T test was used to assess the effects of Myo-Inositol before treatment and after six months of treatment. Result: The significant relation (0.001) was observed between the intervention and PCO and its related symptoms. An evident effect was noticed in each individual after the intervention was provided to them. The relatable symptoms such as irregularities in menses, hirsutism,weight and insulin resistance were reduced by significant ratio. Conclusion: Myo – inositol has proven to be effective in reducing the PCO and its relatable symptoms in young females. Despite the limitations, enough evidence was collected that indicated a significant effect of the intervention