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dc.contributor.author | Nausheen Adnan | |
dc.contributor.author | Uzma Bukhari | |
dc.contributor.author | Iffat Raza | |
dc.date.accessioned | 2019-01-07T05:07:27Z | |
dc.date.available | 2019-01-07T05:07:27Z | |
dc.date.issued | 2019-01-01 | |
dc.identifier.issn | 2220-7562 | |
dc.identifier.uri | http://hdl.handle.net/123456789/8179 | |
dc.description.abstract | Objective: To evaluate weight changes on the liver of male (albino wistar) rats induced by erythromycin. To assess the outcome of aqueous Neem leaf extract on erythromycin induced hepatic injuries. Methodology: Eighty male albino wistar rats were taken randomly and were divided into 4 groups of 20 animals each. Group A as a control group. Group B rats were treated with erythromycin drug. Group C rats were treated with erythromycin along with Aqueous Neem leaves extract. Group D were given only Aqueous Neem leaves extract. Body weight of animals was recorded initially and also after experimentation. After 14 days animals were sacrificed, liver weight was also recorded. Results: The liver of erythromycin treated animals group B were little bigger in size and more reddish. However erythromycin plus Neem treated animals of group C livers were almost like liver of control group A and only Neem given group D animals, liver were exactly same appearance like control group A.Rise in absolute and relative weight of liver was because of drug toxicity. Conclusion: Its established from this recent study that Aqueous Neem leaves extract being a powerful antioxidant, decreased oxidative stress and hepatic injury caused by erythromycin. | en_US |
dc.description.sponsorship | JBUMDC | en_US |
dc.language.iso | en | en_US |
dc.publisher | Bahria University Medical and Dental College Karachi | en_US |
dc.relation.ispartofseries | 9;1 | |
dc.subject | Erythromycin, Hepatotoxicity, Azadirachta indica (Neem) | en_US |
dc.title | Evaluation Of Weight Changes On Wistar Rats Induced By Erythromycin And Aqueous Neem Leaves Extract | en_US |
dc.type | Article | en_US |