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Thesis/Dissertation Repository Medical and Dental College
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(Bahria University Health Sciences Campus Karachi, 2025-12-01)Coronary artery bypass grafting (CABG) remains the gold standard for the treatment of multivessel coronary artery disease, yet long-term success largely dependsongraft patency. Arterial conduits such as the left internal ...
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(Bahria University Health Sciences Campus Karachi, 2025-06-01)Diabetic Retinopathy (DR) is a prevalent complication of Diabetes mellitus (DM) that primarily affects the microvasculature of the retina. However, the early stages of retinal microvascular changes can be challenging ...
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(Bahria University Health Sciences Campus Karachi, 2025-11-01)Triple-negative breast cancer (TNBC) is an aggressive subtype of breast carcinoma characterized by the absence of estrogen receptor (ER), progesterone receptor (PR), and HER2 expression, commonly associated with germline ...
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(Bahria University Health Sciences Campus Karachi, 2025-12-01)Cancer stem cells (CSCs) play a major role in development, progression and in aggressive chemo-resistant behavior as they provide a continuous pool for clonal proliferation of malignant cells. LGR5, one of the most ...
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(Bahria University Health Sciences Campus Karachi, 2025-11-01)Staphylococcus aureus and Streptococcus pyogenes are part of normal flora of human body. Both of them can form a biofilm. Biofilm is described as an adhered collection of immobile groups of microbes fenced within ...
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(Bahria University Health Sciences Campus Karachi, 2025-12-01)Hepatic steatosis, or the buildup of extra fat in the liver, is a hallmark of nonalcoholic fatty liver disease (NAFLD), a group of liver disorders that affect people who drink little or no alcohol. Metabolic risk factors ...
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(Bahria University Health Sciences Campus Karachi, 2025-12-01)Type 2 diabetes mellitus (T2DM) is a growing global health challenge, imposing significant disease burden and economic strain. In Pakistan, the situation is particularly alarming. According to the most recent IDF Atlas ...
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(Bahria University, 2025-12-01)Ischemic stroke (IS) is a leading cause of disability and mortality worldwide, disproportionately affecting populations in low- and middle-income countries (LMICs) such as Pakistan. Despite advances in diagnostics and ...
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(Bahria Unversity Health Sciences Karachi Campus, 2024-11-01)Chronic obstructive pulmonary disease (COPD) is a debilitating disease characterized by progressive airflow obstruction. The cornerstones of treatment are bronchodilator drugs of two different classes including beta ...
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(Bahria Unversity Health Sciences Karachi Campus, 2024-11-01)Chronic otitis media is a disease affecting middle ear of the patient. In this disease, fluid accumulation causes erosion of middle ear ossicles and surrounding structures including sigmoid sinus, jugular bulb and ...
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(Bahria Unversity Health Sciences Karachi Campus, 2024-10-01)Migraine is the most common neurological condition seen in primary care. Globally its affects 2% of population (out of which 1.5% are female and 0.5% are male). Migraine is an episodic and complex sensory processing ...
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(Bahria Unversity Health Sciences Karachi Campus, 2024-10-01)The most common and debilitating complication associated with type 2 diabetes mellitus (T2D) is diabetic foot ulcer (DFU), which can increase morbidity, amputation, and the burden on the health system. It begins with ...
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MMP-8, IL-6 AND IL-1 Β: THE MOST PROMISING SALIVARY BIOMARKERS FOR EARLY DIAGNOSIS OF PERIODONTITIS (Bahria Unversity Health Sciences Karachi Campus, 2024-09-01)Periodontal disease is a chronic inflammatory condition affecting the supporting structures of teeth, which if left untreated, worsens gradually and can have serious consequences on the periodontium. There are several ...
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(Bahria Unversity Health Sciences Karachi Campus, 2024-10-01)Cervical Cancer (CC) is the fourth most common type of cancer worldwide. In vast majority of cases, it is caused by Human Papillomavirus (HPV) - a Sexually Transmitted Disease (STD). In Pakistan, the incidence of ...
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(Bahria Unversity Health Sciences Karachi Campus, 2024-11-01)Polycystic ovarian syndrome (PCOS) is the leading cause of female infertility due to anovulation. Another condition that has a significant impact on ovarian health is hypothyroidism. Both these conditions are widely ...
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(Bahria Unversity Health Sciences Karachi Campus, 2024-11-01)Acute pancreatitis is a sudden inflammation of the pancreas, which is characterized by the activation of pancreatic enzymes and auto digestion of the gland itself. It is becoming a prevalent disease in western as well ...
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(Bahria Unversity Health Sciences Karachi Campus, 2024-11-01)Primary liver tumours are significantly influenced by hepatocellular carcinoma, a diverse liver disease. Clinically, this carcinoma presents with obstructive jaundice, pyogenic liver abscess, and hepatic encephalopathy ...
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(Bahria Unversity Health Sciences Karachi Campus, 2024-10-01)Background: Current standards for assessing mitral valve dimensions are predominantly based on data from Western populations, which may not be applicable to diverse demographic settings. This study aims to establish ...
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(Bahria University Health Sciences college Karachi, 2023-10-01)Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of Nitric oxide (NO) production. It is synthesized by post translational modification of L-arginine which involves the set of enzymes called protein arginine ...
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(Bahria University Health Sciences college Karachi, 2023-10-01)The increase in the prevalence of the varicose vein has opened the gates for further research and exploration on this particular topic. The association between varicose veins and increased levels of inflammatory ...