Comparison of Outcome and Quality of life between Breast Conserving Surgery and Modified Radical Mastectomy for Breast Cancer

Abstract

Objectives: To compare the clinical outcomes, recurrence rates, post-operative complications, and quality of life between patients undergoing BCS and MRM for early-stage breast cancer. Study Design and Setting: This was a prospective cohort study (comparative) conducted at DHQ Teaching hospital Narowal Methodology: This one-year study (January 2023–January 2024) included 93 early-stage breast cancer patients, with 46 undergoing MRM and 47 BCS. Demographics, tumor traits, recurrence rates, complications, and quality-of-life outcomes were analyzed. Statistical tests, including chi-square were performed using SPSS version 20. Results: Complications occurred in 18.1% (17 out of 93) patients in which 7 (14.9%) were from the BCS group, and 10 (21.7%) were from the MRM group. Recurrence rate was 10.9% in MRM group and 4.3% for the BCS group (P<.05). Wound infection was more common in the MRM group (6.5%) compared to the BCS group (4.3%), though this difference was not statistically significant (p = 0.41). Tests of quality of life at the end of a year revealed that BCS patients have far better body image and mental health findings than MRM patients. Conclusion: Although BCS offers higher quality-of- life results, both BCS and MRM are appropriate surgical choices for early-stage breast cancer. These findings make BCS appear like a reasonable choice compared to MRM, More research is advised using larger samples.