Abstract:
Background: Across the globe, traumatic injuries remain one of the foremost reasons for
emergency department attendance and surgical intervention. Although you gain valuable
insights through direct clinical evaluation, confirming the precise nature, timing as well as
complications of any traumatic lesions is only possible by performing thorough
histopathological analysis of the tissues involved.To assess the histopathological
characteristics of traumatic tissue specimens and evaluate their diagnostic utility in relation
to clinical findings.
Methods: This cross-sectional study was conducted at Jinnah Medical College and its
affiliated teaching hospitals from January 2023 to January 2024. A total of 72 patients with
trauma-related soft tissue injuries were included. Tissue specimens obtained through excision,
incision, or resection were processed and analyzed microscopically. Variables assessed
included type of inflammation, necrosis, hemorrhage, fibrosis, healing phase, and presence
of foreign body reaction. Statistical analysis was performed using SPSS version 26.
Results: The majority of patients were male (55.6%) and from rural areas. Firearm and blunt
trauma were the most common injury types. Histologically, acute inflammation (47.2%) and
necrosis (65.3%) were predominant findings. A strong association was found between injury
duration and histological healing stage (p < 0.05). Final diagnoses included traumatic
granuloma (37.5%), infected wounds (31.9%), and organizing hematomas (30.6%).
Conclusion: Histopathological examination plays a critical role in confirming traumatic
injury patterns, estimating the age of lesions, and identifying complications such as infection
or foreign body reactions. Its use complements clinical diagnosis and is particularly valuable
in surgical planning and medico-legal documentation.
