Effect Of Intravenous Iron Therapy on Serum Ferritin and Haemogobin Levels in Children Reporting with Iron Defeciency Anaemia

Abstract

Objective:To evaluatetheeffect of intravenous Iron therapy on serum Ferritin and Haemoglobin levelsinchildrenwith iron deficiency anaemia.Study Design:Cross sectionalstudy.Place and Duration of Study:Combined Military Hospital(CMH),Quetta,from Aug 2015 to Jul 2017.Methodology:Patients of either sex with age 1 to 12 years with iron deficiency anemia were included in the study. Sampling techniquewas Consecutive non-probability purposive sampling. Iron deficiency anemia was diagnosed on the basis of mean corpuscular volume (MCV), Hemoglobin (hb) concentration and serum ferritin. Intravenous iron therapy was given to all patients included in the study. Patients were followed up after 4 weeks. Paired t-test was applied for preand posttherapy HB and serum Ferritin. A p-value ≤0.05 was considered significant.Results:Total number of patients included in the study was55. Out of total patients male were 35 (64%) andfemale were 20 (36%). Mean age of patients was 2.48±1.89 years. Pre therapy Hb and serum ferritin were 8.13±1.96 g/dl and 8.87±10.24, respectively. Post therapy HB and serum ferritin were11.06±93g/dl and 52.60 ±28.61respectively. When paired t test was applied, the p-value was foundstatistically significant <0.05.Conclusion:Intravenous iron therapy effectively improved serum ferritin and Hb concentration in patients with iron deficiency anemia.