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Browsing Published Article (Research) by Issue Date

Browsing Published Article (Research) by Issue Date

Now showing items 1-20 of 53

Synergistic effects of iron deficiency and lead exposure on blood lead levels in children

Dilshad Ahmed Khan; Wafa Munir Ansari; Farooq Ahmad Khan (2011)
Pro/Anti-Inflammatory Cytokines in the Pathogenesis of Premature Coronary Artery Disease

Dilshad Ahmed Khan; Wafa Munir Ansari; Farooq Ahmed Khan (Journal of Interferon & Cytokine Research, 2011)

Proinflammatory interleukin-18 (IL-18), high-sensitivity C-reactive protein (hS-CRP), tumor necrosis factor-alpha (TNF-alpha), and anti-inflammatory IL-10 are involved in the pathogenesis of atherosclerosis. The aim of ...
Injudicious use of laboratory facilities in tertiary care hospitals at Rawalpindi, Pakistan : a cross-sectional descriptive study

Muhammad Farooq Malik; Dilshad Ahmed Khan; Wafa Munir Ansari; Farooq Ahmad Khan (BMC Health Services Research, 2013)

Background: In recent years inappropriate and excessive use of clinical laboratory facilities has become a cause of concern and has led to concurrent rise in the laboratory errors and the health care costs. The aim of the ...
Pesticide Exposure and Endocrine Dysfunction in the Cotton Crop Agricultural Workers of Southern Punjab, Pakistan

Dilshad A Khan; Karam Ahad; Wafa M. Ansari; Hizbullah Khan (2013)

This study evaluated pesticide effects on reproductive and thyroid hormones of cotton farmers of southern Punjab, Pakistan. A total of 88 cotton farmers (42 spray applicators and 46 cotton pickers) were randomly included ...
Prevalence and Trends of Hepatitis B, Hepatitis C and Human Immunodeficiency Viruses among Blood Donors in Islamabad, Pakistan 2005-2013

Hasan Abbas Zaheer, Umar Saeed; Yasir Waheed, Saira Karimi; Usman Waheed (Journal of Blood Disorders and Transfusion, 2014)

Background: Pakistan is a developing country of 190 million people with increased burden of infectious diseases. Hepatitis B virus (HBV), Hepatitis C virus (HCV) and Human Immunodeficiency virus (HIV) are the most important ...
Pharmacological effects of Ibuprofen on learning and memory, Muscarinic receptors genes expression and APP isoforms levels in Prefrontal cortex of AlCl3induced toxicity mouse model

Aisha Nasir Hashmi, Ahmed Yaqinuddin, Touqeer Ahmed (International Journal of Neuroscience, 2014)

Aluminium metal (Al) has been implicated in etiology of many neurodegenerative diseases, most commonly the Alzheimer’s disease (AD). Al causes the biochemical defects, by affecting the neurotransmitters levels, causes ...
Premature Coronary Artery Disease : Potential Role of a 13 SNP Gene Risk Score in the Risk Prediction of Pakistani Patients

Dr. Wafa Munir Ansari; Prof. Dr. Abdul Khaliq Naveed; Prof. Dr. Dilshad Ahmed Khan (The Professional Medical Journal, 2015)

Introduction: Genetic information which is specific to an individual has the potential to improve Coronary Artery Disease (CAD) risk prediction. 13 CAD risk SNPs were selected by removing SNPs in loci which had not been ...
Influence of Interleukin-6 (-174 G/C) Single Nucleotide Polymorphism on Serum IL-6 Levels in Premature Coronary Artery Disease

Wafa Munir Ansari; Abdul Khaliq Naveed; Dilshad Ahmed Khan (Khyber Medical University Journal, 2015)

OBJECTIVES: To evaluate role of Interleukin-6 (-174 G/C) gene promoter polymorphism and the serum level of (IL-6) in the identification of premature coronary artery disease (PCAD). METHODS: The case-control study was ...
Comparison of Ultrasound Therapy and Local Steroid Injection for Treatment of Carpal Tunnel Syndrome using Electrodiagnostics

Omer Jamshed Khan; Naveed Mumtaz; Wafa Munir Ansari (International Journal of Pathology, 2016)

Introduction: To determine the efficacy of ultrasound therapy as compared to intra lesional steroid injection in Carpal Tunnel Syndrome (CTS) using visual analogue scale (VAS) and electrodiagnostic parameters. Study Design: ...
Role of Cytokine Gene Score in Risk Prediction of Premature Coronary Artery Disease

Wafa Omer; Abdul K. Naveed; Omer J. Khan; Dilshad A. Khan (Genetic Testing and Molecular Biomarkers, 2016)

Aims: Pro- and anti-inflammatory cytokines play a significant role in early atherosclerosis. Linkage disequilibrium patterns differ between ethnic groups pointing toward the need to develop population-specific gene risk ...
Premature Coronary Artery Disease; Association of IL-6 Receptor Gene Polymorphism ASP358ALA (A>CRS8192284) with Pro-Inflammatory Cytokines and Cytokine Mediator Serum Levels

Dr. Wafa Munir Ansari; Prof. Dr. Abdul Khaliq Naveed; Dr. Muhammad Nadir Khan; Dr. Omer Jamshed Khan; Prof. Dr. Dilshad Ahmed Khan (The Professional Medical Journal, 2016)

Objectives: Interleukin-6 receptor (IL-6R) gene (A>C, rs8192284) polymorphism has been associated with inflammatory biomarkers. We sought to investigate the association of IL-6R gene (A>C, rs8192284) polymorphism with IL-6, ...
Quality of Life in Spinal Cord Injury : Experience at a Military Tertiary Care Hospital

Omer Jamshed Khan; Nadeem Ahmed; Wafa Munir Ansari (International Journal of Pathology, 2017)

Background: Spinal Cord Injury can have devastating consequences on an individual’s physical and social capabilities. There is a scarcity of studies in Pakistan which identify the factors having a favorable and unfavorable ...
Effect of Coronary Artery Disease risk SNPs on serum cytokine levels and cytokine imbalance in Premature Coronary Artery Disease

Wafa M. Ansari; Steve E. Humphries; Abdul K. Naveed; Abdul K. Naveed; Dilshad A. Khan; Ejaz Hassan Khattak (Elsevier (Cytokine), 2017)

Background: Premature Coronary Artery Disease (PCAD) occurs almost a decade earlier in the South Asian population as compared to the West. Inclusion of genetic information can prove to be a robust measure to improve early ...
Influence of cytokine gene polymorphisms on proinflammatory/anti-inflammatory cytokine imbalance in premature coronary artery disease

Wafa Munir Ansari; Steve E Humphries; Abdul Khaliq Naveed; Omer Jamshed Khan; Dilshad Ahmed Khan (Oxford Academic (Postgraduate Medical Journal (PMJ)), 2017)

Background Genetic information has the potential to create a more personalised, prompt, early and accurate risk evaluation. The effect of these genetic variants on the serum biomarker levels (phenotype) needs to be studied ...
Premature Coronary Artery Disease : Interplay of Immune-Inflammatory Genomics in the Pathogenesis of PCAD

Wafa Omer; Amer Siddiq; Omer Jamshed Khan; Dilshad Ahmed Khan; Ejaz Hassan Khan Khattak; Abdul Khaliq Naveed (The Professional Medical Journal, 2018)

ABSTRACT… Introduction: Integrative genomics may help in the identification of novel biological pathways in the pathogenesis of CAD. Objectives: To find out the association of 5 Cytokine SNPs and 13 CAD SNPs gene risk ...
Comparative Biochemical Analysis of High and Low Sucrose Accumulating Sugarcane Varieties at Formative Stage under Heat Stress

Faisal MEHDI, Kazim ALI; Nesheman HUMA, Iqbal HUSSAIN; Abid AZHAR, Saddia GALANI (Journal of Agricultural Sciences, 2019-02-11)

Sugarcane (Saccharum officinarum L) is a valuable cash crop which plays an imperative role in the worldwide economy. However, high temperature has significantly retarded the crop growth and yield by alteration of biochemical ...
Genetic Diversity of Human Immunodeficiency Virus TypeJ in Asymptomatic Blood Donors in Islamabad, Pakistan

Usman Waheed, Farooq Ahmed Noor; Noore Saba, Akhlaaq Wazeer; Zahida Qasim, Muhammad Arshad; Saira Karimi, Ahmad Farooq; Javaid Usman, Hasan Abbas Zaheer (Journal Lab Physicians, 2020)

Objective The serological testing of human immunodeficiency virus (HIV) is mandatory under the blood safety legislation of Pakistan; hence, data exist on the prevalence of HIV in blood donors. However, little is known ...
Special Pathology in the course content of third year MBBS : views of students and teachers

Riaz Shahbaz Janjua; Jamilah Riaz; Wafa Omer (Pakistan Journal of Medical Sciences, 2020)

Objective: The students and teachers are major stakeholders whenever there is a change in the curriculum. Objective of the study was to assess the views of Third Year MBBS students and college teachers involved in teaching ...
Synthetic β‑hydroxy ketone derivative inhibits cholinesterases, rescues oxidative stress and ameliorates cognitive deficits in 5XFAD mice model of AD

Syed Ilyas Ahmad · Gowhar Ali · Tahir Muhammad · Rahim Ullah · Muhammad Naveed Umar · Aisha Nasir Hashmi (Molecular Biology Reports, 2020)

Alzheimer’s disease (AD) is a progressive, chronic and age-related neurodegenerative disorder that affects millions of people across the world. In pursuit of new anti-AD remedies, 2-[Hydroxy-(4-nitrophenyl)methyl]-cyclopentanone ...
Preventive Effect of Turmeric against Anti-Mosquito Smoke Induced Pulmonary Fibrosis in Laboratory Rat

Saira Jawed; Wafa Omer (Journal of Islamic International Medical College (JIIMC), 2020)

Objective: To appraise the preventive effect of turmeric on anti-mosquito coil smoke induced interstitial fibrosis in lungs of Sprague Dawley rats. Study Design: Randomized control trial. Place and Duration of Study: ...

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