Huma Amin, Shameela Majeed, Wafa Omer, Shumaila Najeeb, Nadia Wali, Fatima tuz Zuhra(The Professional Medical Journal, 2025)
Objective: To compare the hematological and biochemical parameters of dengue patients within different
serological markers. Study Design: Cross Sectional study. Setting: Carried out in a Tertiary Care Hospital at ...
Tayyaba Hussain1, Yasmin Badshah1*, Maria Shabbir1, Fizzah Abid1, Ghulam Murtaza Kamal1, Amna Fayyaz1, Janeen H. Trembley, Tayyaba Afsar, Fohad Mabood Husain and Suhail Razak(Cancer Cell International, 2024)
Background Hepatocellular carcinoma (HCC) is a global health concern. Due to late diagnosis and limited
therapeutic strategies, HCC based mortality rate is exponentially increasing globally. Genetic predisposition is ...
Fizzah Abid, Khushbukhat Khan, Yasmin Badshah, Naeem Mahmood Ashraf, Maria Shabbir, Arslan Hamid, Tayyaba Afsar, Ali Almajwal and Suhail Razak(Cancer Cell International, 2023)
Background PRKCG encodes PKC γ, which is categorized under the classical protein kinase C family. No studies have
specifically established the relationship between PRKCG nsSNPs with structural and functional variations ...
Tayyaba Hussain, Yasmin Badshah, Maria Shabbir, Fizzah Abid , Dilawar Khan, Janeen H. Trembley, Tayyaba Afsar, Ali Almajwal, Suhail Razak(Computers in Biology and Medicine, 2025)
A single-nucleotide polymorphism (SNP) is a naturally occurring variation in genomic DNA.
Untranslated regions (UTRs) are involved in the regulatory pathways of cells that influence transcriptional and
translational ...
Aamir Ijaz, Seyyedha Abbas, Maria Shabbir, Yasmin Badshah, Fizzah Abid, Tayyaba Afsar and Suhail Razak(Orphanet Journal of Rare Diseases, 2025)
Inherited metabolic disorders (IMDs) are classified under rare genetic diseases almost always presenting in newborn
and infants. IMDs are classified according to the clinical presentation, diagnosis and prognosis. Several ...
Fizzah Abid, Khushbukhat Khan, Naeem Mahmood Ashraf, Yasmin Badshah, Maria Shabbir, Janeen H Trembley, Tayyaba Afsar, Ali Almajwal, Suhail Razak(Journal of Cancer, 2024)
The changes in the protein kinase C gamma gene (PRKCG) expression are associated with both coding and
non-coding variants. No studies have specifically established the association between PRKCG 3′UTR, 5′UTR,
donor and ...
Aneela Mustafa, Maria Shabbir, Yasmin Badshah, Khushbukhat Khan, Fizzah Abid, Janeen H. Trembley, Tayyaba Afsar, Ali Almajwal and Suhail Razak(BMC Cancer, 2024)
Background Variations in untranslated regions (UTR) alter regulatory pathways impacting phenotype, disease
onset, and course of disease. Protein kinase C Zeta (PRKCZ), a serine-threonine kinase, is implicated in ...
Fizzah Abid, Talha Iqbal, Khushbukhat Khan, Yasmin Badshah, Janeen H Trembley, Naeem Mahmood Ashraf, Maria Shabbir, Tayyaba Afsar, Ali Almajwal and Suhail Razak(Biomarker Research, 2022)
Background: HCC is a major health concern worldwide. PKC gamma, a member of the conventional PKC subclass,
is involved in many cancer types, but the protein has received little attention in the context of single ...
Aisha Nasir Hashmi 1, Rizwan Taj 2, Zehra Agha 1,3, Raheel Qamar , Jamal B. Williams , and Maleeha Azam(Biomedicines, 2025)
Background: Monoamine oxidase A (MAOA) has a role in metabolising different
biogenic amines, including dopamine. Functional studies have revealed the effect of
promoter region variants on the transcriptional activity of ...
Background: The dopaminergic pathways control neural signals that modulate mood and behaviour
along and have a vital role in the aetiology of major depression (MDD), schizophrenia (SHZ) and
bipolar disorder (BD). Genome-wide ...
Aisha Nasir Hashmi · Raheel Qamar · Rizwan Taj · Usama Bin Zubair · Zehra Agha · Saddam Akber Abbasi· Maleeha Azam(European Archives of Psychiatry and Clinical Neuroscience, 2023)
With an increasing incidence of psychiatric disorders worldwide, there is a need for a better understanding of the populationspecific
contributing risk factors that are associated with common psychiatric conditions. This ...
Aisha Nasir Hashmi, Raees Ahmed Dharejo, Usama Bin Zubair, Netasha Khan, Iqra Kashif, Muhammad Ajmal, Rizwan Taj, Raheel Qamar & Maleeha Azam(International Journal of Neuroscience, 2022)
Aim: Dopamine β-hydroxylase (DBH) is a copper-containing enzyme that has an important role
in maintaining the cellular homeostasis between the two neurotransmitters, dopamine (DA) and
nor-adrenaline (NA). DBH functional ...
Sliha Awan · Aisha N. Hashmi · Rizwan Taj · Sadaf Munir · Rabia Habib · Sajida Batool · Maleeha Azam · Raheel Qamar · Syed M. Nurulain(Biochemical Genetics, 2021)
Major depressive disorder (MDD) is characterized as clinical depression, which
primarily affects the mood and behaviour of an individual. In the present study
butyrylcholinesterase (BChE), a co-regulatory cholinergic ...
Syed Ilyas Ahmad · Gowhar Ali · Tahir Muhammad · Rahim Ullah · Muhammad Naveed Umar · Aisha Nasir Hashmi(Molecular Biology Reports, 2020)
Alzheimer’s disease (AD) is a progressive, chronic and age-related neurodegenerative disorder that affects millions of people
across the world. In pursuit of new anti-AD remedies, 2-[Hydroxy-(4-nitrophenyl)methyl]-cyclopentanone ...
Aisha Nasir Hashmi, Ahmed Yaqinuddin, Touqeer Ahmed(International Journal of Neuroscience, 2014)
Aluminium metal (Al) has been implicated in etiology of many neurodegenerative
diseases, most commonly the Alzheimer’s disease (AD). Al causes the biochemical
defects, by affecting the neurotransmitters levels, causes ...
Huma Amin, Shameela Majeed, Wafa Omer, Shumaila Najeeb, Nadia Wali, Fatima tuz Zuhra(The Professional Medical Journal, 2025)
Objective: To compare the hematological and biochemical parameters of dengue patients within different serological markers. Study Design: Cross Sectional study. Setting: Carried out in a Tertiary Care Hospital ...
Saira Karimi, Muhammad Ali Nawaz, Saadia Naseem, Zahid Ali(PLOS One, 2025-05-14)
Plants native to colder climates, higher elevations, or semi-arid regions have more
phenolic compounds in their organs. Faced with the current climate crisis, the effects
of global heating with overgrazing pressure on ...
High quality RNA is critical for molecular and viral diagnostic applications. In case of citrus, polyphenol and polysaccharide rich
content hinders many RNA isolation methods causing low quality RNA. These shortcomings ...
B. Saleh, N. Huma; S. Galani(Journal of Animal & Plant Sciences, 2023-06-18)
Brazzein- a low-calorie natural sweetener is an effective substitute for deleterious effects of sucrose. Uptill now, limited
production of recombinant brazzein protein using heterologous expression system along with ...