Published Articles (Pharmacology): Recent submissions

Now showing items 21-28 of 28

Relaxant effect of pioglitazone on the guinea-pig isolated trachea through the modulation of endogenous prostaglandins

Naila Abrar, Ayesha Janjua; Sarwat Jahan, Manzoor Khan; Sarah Zahid, Asma Khan (IRANIAN JOURNAL OF PHARMACOLOGY & THERAPEUTICS, 2019-06-29)

Thiazolidinediones are commonly used anti-diabetic drugs. Owing to the antiinflammatory action of TZDs as a result of there action on the PPAR gamma receptor and a proposed action on the prostaglandins, these drugs can ...
A Comparative Study to Evaluate the Chronotropic Action of Citalopram, Fluoxetine and Paroxetine on Intact Frog’s Heart

Ayesha Shahnawaz, Naila Abrar; Munir Ahmad Khan (Medical Forum Monthly, 2016-04-27)

Objective: To compare the chronotropic action of citalopram, fluoxetine and paroxetine on frog heart. Study Design: Experimental animal study Place and Duration of Study: This study was conducted at Yusra Medical and ...
Rosiglitazone Induced Smooth Muscle Relaxation and Reversal Via L-Bisphenol A Diglycidyl Ether

Sarwat Jahan, Manzoor Khan; Haseeba Mukhtar, Naila Abrar; Sarah Zahid, Susan Kakakhel (International Journal of Pathology, 2022)

Background: PPAR-γ (Peroxisome Proliferator Activated receptor gamma) ligands are capable of suppressing the expression of a variety of genes involved in inflammation present in the macrophages upon activation and carry ...
Reversal of Loperamide Induced Intestinal Smooth Muscle Relaxation by Glibenclamide and Repaglinide in Vitro

Javaria Arshad, Naila Abrar; Munir Ahmad Khan, Sarwat Jahan (Medical Forum Monthly, 2014)

Objective: To compare the inhibitory effects of Glibenclamide and Repaglinide on loperamide induced relaxation of isolated ileum of Rabbit. Study Design: Comparative controlled in-vitro experimental Study. Place and ...
Nitric Oxide Pathway-Mediated Relaxant Effect of PPAR (Peracisome Proliferator Activated Receptor)-Gamma Agonist In The Guinea-Pig Isolated Trachea.

Naila Abrar, Ayesha Janjua; Sarwat Jahan, Zarafshan Badar; Asma Khan, Fatima Qasim (The Professional Medical Journal, 2020-01-01)

Objectives: This study focuses on the role of the mediator of smooth muscles i.e. nitric oxide in the effect of rosiglitazone on the relaxation of contractions in guinea pig trachea induced by histamine. Study Design: ...
A Comparative Study to Evaluate Chronotropic and Inotropic Effects of Nimodipine and Verapamil on Intact Frog's Heart

Javaria Arshad, Naila Abrar; Munir Ahmad Khan (Foundation University Medical Journal, 2014)

Background: Nimodipine and verapamil are calcium channel blocking drugs. These drugs differ chemically hence their pharmacological actions are also different. Verapamil has predominant action on myocardial calcium channels ...
Role Of Nitric Oxide in the Effect of Nebivolol on Isolated Tracheal Muscle of Guinea Pig

Asma Shaukat, Naila Abrar; Ayesha Naureen, Muhammad Nawaz (Journal of Ayub Medical College Abbottabad, 2013)

Background: The use of beta blockers is limited by their ability to produce bronchospasm in asthmatics. Third generation β-blockers like Nebivolol may show better tolerability because they may augment the release of ...
Traditional to Modular, System-Based Learning: Our First Experience

Talat Ahmed, Naila Abrar; Faiza Shuja, Umair Malik (Rawal Medical Journal, 2010)

Objective: To determine how far we were successful with modular, integrated system-based learning adopted in our institution since 2008. Methods: A retrospective study was carried out to compare traditional and modular ...

Now showing items 21-28 of 28

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