Routine Histopathology of Surgically Resected Gallbladder - A multicenter surgical audit

Abstract

Background: Occurrence of Gall Bladder diseases are common and they are presented with variety of different histopathological conditions. Cholelithiasis is attributed to both inflammatory and malignant diseases. The purpose of this study was to investigate demographic profiles of patients as well as histopathological presentation of surgically resected specimens of elective cholecystectomies. Methods: This retrospective study was conducted on total 647 specimens collected at department of pathology at two tertiary care hospitals over the period of 3 years. Patient record were used to extract clinical and histopathological data. Results: In total, there were 647 participants that included 68.6% females and 31.4% males. Average age of study participants was 44.8±15.2 years. Around 92.9% of the cases presented with cholelithiasis. Among all, the most common pathology was chronic cholecystitis (89.8%) whereas only one case was identified with malignancy. Conclusion: The findings of current study suggest that one should promote both intra-operative and macroscopic examination to reveal presence of malignant condition. Though, it does not challenge importance of histopathological examination of surgically resected specimens of elective cholecystectomies.