How to Choose Right Medication?

Abstract

Obesity is physical as well as psychological problem in human population. Dyslipidemia is alteration of normal levels of good and bad cholesterol in human body. It can cause heart diseases like hypertension, cardiac arrhythmias, and heart attack. Niacin, Statins, BABR and jibrates are used to normalize dyslipidemia, Medicinal herbs have been researched and found effictive to normalize plasma lipids with different characteristics. OBJECT OF RESEARCH Aim of this research was to compare individual and combined efficts of Ispaghola and Anjeer in primary as well as secondary hyperlipidemia, DESIGN: It was single blind placebo-controlled research work, conductedfrom March 2018 to September 2018 at General Hospital, Lahore, Pakistan. SAMPLE SIZE: One hundred male and female hyperlipidemic patients were selected for research, age range from 20 to 65 years, Inclusion criteria were primary, secondary hyperlipidemic patients, Written and explained consent was taken from all participants and approved by research ethics committee of the hospital. Patients were divided in four equal groups, comprising 25 patients in each group. METHOD: Their baseline systolic/diastolic blood pressure and lipid projile was estimated and kept in individual'sfo/der. Group-I was on Ispaghula iO grams, group-II was on 10 grams Anjeer, and group-Ill was advised to take IO grams ispaghula, and 10 grams Anjeer in combination for 3 months. Group-IV was on placebo therapy, RESULTS: After 3 months when results were compiled and I analyzed statistically, it was observed that 1spaghula decreased LDL-c significantly with p-value <0.05, Anjeer decreased LDL-c significantly with p-value <0. 01. When both herbs were combinely given, they reduced systolic BP with p-value <0.01, LDL-c reduced highly significantly with p-value <0,001, and HDLc increased significantly with p-value <0,05. CONCLUSiON: It was concluded from the study that Ispaghula and Anjeer have LDL-c lowering potential if given separately. When used in combination they reduce systolic BP, LDL-c, and increase HDL-c.