Abstract:
Obesity is physical as well as psychological problem in human population. Dyslipidemia is alteration of
normal levels of good and bad cholesterol in human body. It can cause heart diseases like hypertension,
cardiac arrhythmias, and heart attack. Niacin, Statins, BABR and jibrates are used to normalize
dyslipidemia, Medicinal herbs have been researched and found effictive to normalize plasma lipids with
different characteristics. OBJECT OF RESEARCH Aim of this research was to compare individual and
combined efficts of Ispaghola and Anjeer in primary as well as secondary hyperlipidemia, DESIGN: It was
single blind placebo-controlled research work, conductedfrom March 2018 to September 2018 at General
Hospital, Lahore, Pakistan. SAMPLE SIZE: One hundred male and female hyperlipidemic patients were
selected for research, age range from 20 to 65 years, Inclusion criteria were primary, secondary
hyperlipidemic patients, Written and explained consent was taken from all participants and approved by
research ethics committee of the hospital. Patients were divided in four equal groups, comprising 25
patients in each group. METHOD: Their baseline systolic/diastolic blood pressure and lipid projile was
estimated and kept in individual'sfo/der. Group-I was on Ispaghula iO grams, group-II was on 10 grams
Anjeer, and group-Ill was advised to take IO grams ispaghula, and 10 grams Anjeer in combination for 3
months. Group-IV was on placebo therapy, RESULTS: After 3 months when results were compiled and
I analyzed statistically, it was observed that 1spaghula decreased LDL-c significantly with p-value <0.05,
Anjeer decreased LDL-c significantly with p-value <0. 01. When both herbs were combinely given, they
reduced systolic BP with p-value <0.01, LDL-c reduced highly significantly with p-value <0,001, and HDLc
increased significantly with p-value <0,05. CONCLUSiON: It was concluded from the study that
Ispaghula and Anjeer have LDL-c lowering potential if given separately. When used in combination they
reduce systolic BP, LDL-c, and increase HDL-c.
