Abstract:
Introduction: Clinical thyroid cancer is uncommon, with an estimated incidence in various parts of the world of 0.5
to 10 cases per 100,000 persons. It accounts roughly for about 0.5% of all cancers in men and 1.5% of all cancers in
women. Aims and objectives: The main objective of the study is to analyze the incidence of multinodular goiter and
follicular carcinoma of thyroid in Pakistan.Material and methods: This cross sectional study was conducted in Yusra
General Hospital during 2018. This study was done with the permission of ethical committee of hospital. The data was
collected from 50 patients of both genders. Demographic information of patients, clinical features and tissue biopsy
results were extracted. All the selected patients underwent ultrasonography and fine needle aspiration cytology in
cases with a suspicions nodule rapidly growing hard, irregular nodule which was detected on clinical examination and
on ultrasound.Results: The data were collected from 50 patients of both genders. The female predominated the male
in the ratio of 7.5:2.5. The most common presenting symptom was swelling in front of neck, which moved with
swallowing. In 85(85%) patients the swelling which was of thyroid origin was benign, while in 15 (15%) patient it
was malignant. Out of all malignant tumors the papillary carcinoma was on the top with a percentage of
10%.Conclusion: It is concluded that the risk of malignancy in multinodular goitre is not as low as it was thought
before and that it is quite significant and is mostly of the papillary type.
