Association of Serum Vitamin D Levels with Senile Cataract

Abstract

Purpose: To determine vitamin D levels in patients of senile cataract and compare them with age related control patients. Study Design: Case control observational study. Place and Duration of Study: Naseer Memorial Hospital, Dadhyal Azad Kashmir from March 2016 to June 2017. Material and Methods: Three hundred patients were selected and two groups were designed for the study. Group I included patients having senile cataract of any morphological type. The inclusion criteria were age of 50 years or more. Group II was control in which age matched controls that had no cataract were enrolled from the outpatient clinic. Vitamin D levels were measured by radioimmunoassay technique with Diasorin SR® kit following the user’s manual. The collected data was entered in the statistical package for social sciences (SPSS) version 21 for analysis. Independent t –test was used to determine the significant difference of means between controls and patients. P value less than 0.05 was considered as significant. Results: Group I consisted of 65.33 % females and 35.66% males whereas in group II were 68% females and 32% males. The mean age of patients was 63.20 ± 9.5 years in group I and 65.5 ± 8.9 years in group II. Statistically no significant difference (p>0.05) was found between mean Vitamin D levels in cataract patients (25.95 ± 3.75 ng/mL vs. and age matched control (29.02 ± 5.11ng/mL). Conclusion: There was no statistically significant difference between the vitamin D levels of cataract patients and the age matched controls.