Abstract:
Aim: To study the age incidence, common pathohistologic subtypes, and clinical presentation of patients with Hodgkin
lymphoma (HL) in local population.
Materials and Methods: This retrospective study was carried out by reviewing medical record for all lymph
nodes biopsies with the diagnosis of HL in Rehman Medical Institute Peshawar from year July 2011 to Jan 2018
Results: Total of 31 lymph node biopsies were examined. Twenty nine (94%) cases were diagnosed with Classical
Hodgkin lymphoma (CHL) and only 2(6%) were diagnosed with nodular lymphocyte predominant (NLPHL) type. Among
all our cases 65% were males and 35% were females and mean age of presentation was 28.42 years. The major site of
lymph node involvement from where biopsy was taken for histological diagnosis was found to be the cervical group of
lymph nodes involving 58% of the cases. Histological subtyping of the cases in the study indicates that mixed cellularity
HL constitute 22 cases (76%) making it the most predominant subtype followed by nodular sclerosis 7 cases (24%).
Conclusion: Patients are predominantly males and the most common presentation was cervical lymphadenopathy.
Major bulk of the patients with Hodgkin lymphoma suffer from classical Hodgkin’s lymphoma and the most dominant
subtype was mixed cellularity Hodgkin’s lymphoma.
