Frequency of Benign and Malignant Breast Lesions: A Histopathological Analysis

Abstract

OBJECTIVE: To evaluate the frequency of benign and malignant breast diseases in females at Pathology Department, Al-Nafees Medical College & Hospital (ANMCH) Islamabad STUDY DESIGN: A Cross sectional study PLACE AND DURATION: From 10th January, 2015 to 20th October, 2015 at Department of Pathology, Al-Nafees Medical College & Hospital (ANMCH) Islamabad. METHODOLOGY: 120 breast specimens collected in a period of 9 months at pathology laboratory, Al-Nafees Medical College & Hospital (ANMCH) Islamabad were fixed in formalin, processed by automated tissue processor. Slides were stained with H&E stain and examined by consultant histopathologist under light microscope. All slides were divided into benign and malignant cases. Malignant cases were further graded according to Modified Bloom and Richardson system. RESULTS: Among total 120 breast specimens, commonest lesion is fibroadenoma (51%) followed by infiltrating duct carcinoma (12.5 %), breast abscess (11.6 %), fibrocystic change (10.8%), mastitis (3.3%) and medullary carcinoma (3.3%). CONCLUSION: Benign breast lesions were more common than malignant lesions in our study. Fibroadenoma was the commonest breast pathology.