Frequency of Oral Candidal Carriage in Type II Diabetic Patients and Association with Acid Peptic Disease

Abstract

OBJECTIVE: To determine the frequency of oral Candidiasis in diabetic patients and to find out the association between APD, dysphagia and gastro esophageal reflux disease in diabetic patients and oral Candidiasis. PATIENTS AND METHODS: It was a Cross sectional study carried out at Pathology (Microbiology) Department of Benazir Bhutto Hospital, Rawalpindi. The sample size was 144 i.e patients having type II diabetes. The data was analyzed by SPSS version 16 for statistical analysis. Chi square test was applied and p value <0.05 was considered significant. METHODOLOGY: Oral swabs of 144 diagnosed patients of Type II Diabetes Mellitus were taken and cultured on Sabourad's agar, stained by lacto phenol blue and confirmed by germ tube test to see the presence of Candida species. RESULTS: The Candida species were isolated from 47.9% (n=69) of patients. Out of which 65.2% (n= 45) were males and 34.7% females (n=24) were females. The mean age of male patients was 47 years and the mean age of female patients was 51years. CONCLUSIONS: Oral Cadidiasis in Diabetics has significant association with Acid Peptic Disease (APD), dysphagia and gastro esophageal reflux disease. Therefore, the oral cavity examination must not be neglected in diabetic patients.