Abstract:
Objective: To determine diagnostic accuracy of chest x-ray for the diagnosis of interstitial lung disease keeping high
resolution computed tomography as gold standard.
Study design and setting: Comparative cross sectional study, Department of Radiology PNS Shifa Karachi
Methodology: Study done over the period of 1 year and two months. 160 Patients were included by using non-probability
consecutive sampling all underwent CXR and HRCT chest. Sample size was calculated using sensitivity and specificity
calculator for sample size with expected sensitivity of 80%7
, expected specificity of 82.98%7
and expected prevalence of
76%7
Results: In this 160 patients were included by using non probability sampling. Among all 116(72.50%) were males while
44 (27.50%) were females. Sensitivity (SE),specificity, positive predictive value (PPV) negative predictive value(NPV)
and diagnostic accuracy of CXR vs HRCT in cases of ILD was 88.89%, 87.50%, 88.89%, 87.50% and 88.24%
respectively.
Conclusion: Chest x-ray has high diagnostic accuracy and simultaneously readily available and cost effective
modality, therefore it can be effectively used as alternative to HRCT
