Welcome to the Bahria University DSpace digital repository. DSpace is a digital service that collects, preserves, and distributes digital material. Repositories are important tools for preserving an organization's legacy; they facilitate digital preservation and scholarly communication.
dc.contributor.author | Shabeer Ahmed | |
dc.contributor.author | Hammad Raziq | |
dc.contributor.author | Noman Sadiq | |
dc.contributor.author | Sana Soomro | |
dc.contributor.author | Rubina Amjad | |
dc.contributor.author | Wazir Ahmed Baloch | |
dc.date.accessioned | 2023-08-03T10:34:54Z | |
dc.date.available | 2023-08-03T10:34:54Z | |
dc.date.issued | 2023-07-01 | |
dc.identifier.issn | 2220-7562 | |
dc.identifier.uri | http://hdl.handle.net/123456789/15888 | |
dc.description.abstract | Objectives: To determine the association of Monocyte chemoattractant protein-1 (MCP-1) level with Age, blood glucose level, Exercise, Gender and Smoking in diabetic retinopathy patients. Study Design and settings: A case-control study was carried in the physiology department at the Jinnah Postgraduate Medical Centre in Karachi From April 2019 to October 2020. Methodology: One hundred people were divided into four groups which were; Group D (n=25) were healthy normal individuals; Group C (n=25) diabetic patient's with moderate retinopathy; Group B (n=25) diabetic patient's with mild retinopathy while Group A (n=25) diabetic patients with no retinopathy. Every participant was checked for blood sugar level, retinoscopy through slit lamp examination and serum MCP-1 level. The association was made between diabetic retinopathy, MCP-1 protein levels, age, gender, smoking and exercise. Results: MCP-1 levels are significantly greater in diabetic males with moderate retinopathy compared to diabetic females with moderate retinopathy (p-value 0.042). Similarly, smoking is associated with the elevation of MCP-1 levels in diabetic patients with moderate retinopathy (p-value 0.05). Exercise has no significant effect on MCP-1 levels in all groups. An increase in age, HbA1C, fasting and random blood glucose levels were significantly correlated with MCP-1 levels ( p value 0.000) Conclusion: It is concluded from the study that an advance in age and an increase in blood glucose level are associated with an increased level of MCP-1 protein. Moreover, Male gender and smoking are also associated with enhanced MCP 1 levels in diabetic patients with moderate retinopathy | en_US |
dc.description.sponsorship | JBUMDC | en_US |
dc.language.iso | en | en_US |
dc.publisher | Bahria University Health Sciences college Karachi | en_US |
dc.relation.ispartofseries | 13;03 | |
dc.subject | Diabetic Retinopathy, Exercise, Gender, Monocyte Chemoattractant Protein-1, Smoking | en_US |
dc.title | Unravelling the Influence of Demographic and Lifestyle Factors on Monocyte Chemoattractant Protein-1 in Diabetic Retinopathy Patients | en_US |
dc.type | Article | en_US |