Effects of Myopia on Visual Evoked Potentials in Patients at Tertiary Care Hospital

Abstract

Objective: To determine the effects of myopia on Visual Evoked Potentials among the subjects attending the eye OPD. Study design and setting: This was a cross-sectional study with non-probability convenience sampling technique carried out at Department of Ophthalmology, Peoples Medical College Hospital Nawabshah / GMMMC Sukkur from March 2021 to November 2021. Methodology: Total sample size was derived to be 180. Diagnosed myopia irrespective of gender and aged 25 to 45 years were included. Optic atrophy, Extensive retinal disease, any neurological disorder like multiple sclerosis, stroke and Visual pathway disorders were excluded. SPSS version 25.0 was used for data analysis. Results: The mean age of the patients was 39.14 ± 6.73 years. There were n=96 (53%) females and n=84 (47%) males. In myopic samples the mean pattern stimuli latency P100 in right eye was 92.07 ±5.1 in cases (without correction) and 82.09 ± 5.8 in controls (with correction) with significant P-value 0.023, while in left eye was 93.55 ± 6.7 in cases (without correction) and 83.6 ± 7.0 in controls (with correction) with significant P-value 0.028. Conclusion: Greater the myopia; greater was the Visual Evoked Potential (VEP) changes with regards to latency and amplitude in pattern stimuli especially P100 being the most affected component in this regard. It is therefore necessary that every patient who goes for VEP test should be corrected for myopic refractive error