IMPACT OF HYDROXYUREA (HU) ON QUALITY OF LIFE (QoL) OF BETA THALASSEMIA PATIENTS: A MODERATING ROLE OF HEALTHCARE PROFESSIONALS’ PERFORMANCE FROM THE VIEWPOINT OF PATIENTS

Abstract

Purpose: The purpose ofthis study was to seek out the impact ofthe drug Hydroxyurea on improving determinants of Quality of Life of BT patients with moderating role of healthcare professionals in private hospital of Karachi. These determinants of Quality of life Physical Health, Emotional/ Psychological Health and Social Health (family and School functioning). As we all know that the quality of life is an important element which requires improvement throughout the life of Beta - Thalassemia patients provided by healthcare professionals, so efforts were made to find out the impact of Hydroxyurea therapy on all these determinants of Quality of Life in Private Hospital with interaction of healthcare professionals. were Methodology & Design: In this research, deductive approach was adopted whereby hypothesis were originated first followed by organizing a well- structured questionnaire as a tool for measuring the data. The nature of research was explanatory, based on primary quantitative data. The data collected through the questionnaire by using Likert scale, with the range of 1-5 and 1-7. The data was collected from a sample size of 290 patients, visited in out - patient department and Marrow was daycare department of National Institute of Blood Diseases and Bone Transplantation Hospital. To analyze the data, Regression and Correlation tests were applied by using IBM SPSS (Statistical Package for Social Sciences) Statistics 23.0. Findings: This study had revealed that the impact ofHydroxyurea therapy on improving the Quality of Life of Beta Thalassemia is not evident as per the analysis whereas by inducing moderating role of healthcare professional performance, the impact of Hydroxyurea not observed significant on physical, psychological, and social health problems of BT patients. Limitations: Since limited time was one of the main constraints for the conduction of this study so (290 responses) were unable to follow for intervals to validate the impact of Hydroxyurea on Quality of Life of Beta Thalassemia patients. Secondly, the research was single center so impact of Hydroxyurea on Quality of Life ofBeta Thalassemia patients with moderating role of healthcare professional’s performance were analyzed in single center and it may have contrasted result when study conducted in multicenter. Thirdly, it only evaluates impact of Hydroxyurea on Quality of Life of Beta Thalassemia patients’ results were more reliable when compared with other hemoglobinopathies. Recommendations: The healthcare professionals were recommended to improve the Quality of Life of Beta Thalassemia patients’ through awareness sessions, proper counseling with multidisciplinary of professionals which include hematologist, endocrinologist psychologist and other paramedical staff for improving determinants of Quality of Life by effecting on their physical, psychological and social health increase their life expectancy and prepare them more inclined towards their well - being.