Abstract:
Purpose:
The purpose ofthis study was to seek out the impact ofthe drug Hydroxyurea on improving
determinants of Quality of Life of BT patients with moderating role of healthcare
professionals in private hospital of Karachi. These determinants of Quality of life
Physical Health, Emotional/ Psychological Health and Social Health (family and School functioning). As we all know that the quality of life is an important element which requires
improvement throughout the life of Beta - Thalassemia patients provided by healthcare
professionals, so efforts were made to find out the impact of Hydroxyurea therapy on all
these determinants of Quality of Life in Private Hospital with interaction of healthcare
professionals.
were
Methodology & Design:
In this research, deductive approach was adopted whereby hypothesis were originated first
followed by organizing a well- structured questionnaire as a tool for measuring the data. The
nature of research was explanatory, based on primary quantitative data. The data
collected through the questionnaire by using Likert scale, with the range of 1-5 and 1-7. The
data was collected from a sample size of 290 patients, visited in out - patient department and
Marrow
was
daycare department of National Institute of Blood Diseases and Bone
Transplantation Hospital. To analyze the data, Regression and Correlation tests were applied
by using IBM SPSS (Statistical Package for Social Sciences) Statistics 23.0.
Findings:
This study had revealed that the impact ofHydroxyurea therapy on improving the Quality
of Life of Beta Thalassemia is not evident as per the analysis whereas by inducing
moderating role of healthcare professional performance, the impact of Hydroxyurea
not observed significant on physical, psychological, and social health problems of BT
patients. Limitations:
Since limited time was one of the main constraints for the conduction of this study so (290
responses) were unable to follow for intervals to validate the impact of Hydroxyurea on
Quality of Life of Beta Thalassemia patients. Secondly, the research was single center so
impact of Hydroxyurea on Quality of Life ofBeta Thalassemia patients with moderating role
of healthcare professional’s performance were analyzed in single center and it may have
contrasted result when study conducted in multicenter. Thirdly, it only evaluates impact of
Hydroxyurea on Quality of Life of Beta Thalassemia patients’ results were more reliable
when compared with other hemoglobinopathies.
Recommendations:
The healthcare professionals were recommended to improve the Quality of Life of Beta
Thalassemia patients’ through awareness sessions, proper counseling with multidisciplinary
of professionals which include hematologist, endocrinologist
psychologist and other paramedical staff for improving determinants of Quality of Life by
effecting on their physical, psychological and social health increase their life expectancy and
prepare them more inclined towards their well - being.
